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Clinical Diagnostic System
Warfarin Genotyping ReagentsWarfarin Genotyping Reagents

Genetic information helpful for dosing estimates.

Warfarin is the most widely prescribed oral anticoagulant for thromboembolic therapy in North America and Europe. Warfarin therapy associated hemorrhage is one of the leading causes of drug related adverse events, including death, in many Western countries. The combination of CYP2C9*2, CYP2C9*3 and VKORC1 genotypes has proved to be effective at helping to determine the appropriate doses of Warfarin.*

 

Benefits of the Warfarin Genotyping Reagents

Warfarin genotyping reagents provide rapid time to result, easy to use format, and is compatible with variety of instrument platforms. It is also priced significantly less than competitive products. Our Warfarin Genotyping Reagents (ASR) provide a fast and effective solution for genotyping samples for the three genotypes listed below.

Warfarin Genotyping Reagents Specifications

Ordering Information
 
Reactions
Catalog Number
CYP2C9*2 Genotyping (Warfarin Target 1) Reagent
100
HRLS-ASY-0007
CYP2C9*3 Genotyping (Warfarin Target 2) Reagent
100
HRLS-ASY-0010
VK1639 Genotyping (Warfarin Target 3) Reagent
100
HRLS-ASY-0011

*Rapid Melting Curve Analysis for Genetic Variants that Underlie Inter-Individual Variability in Stable Warfarin Dosing. Carlquist JF et al. J Thrombosis and Thrombolysis, July 2007

Platform evaluation for rapid genotyping of CYP2C9 and VKORC1 alleles. Joshi VA, Duffy E, Funke BH, Farwell LM, Mancini-Dinardo D and Kucherlapati R. Personalized Medicine, July 2009

Validation of clinical testing for warfarin sensitivity: comparison of CYP2C9-VKORC1 genotyping assays and warfarin-dosing algorithms. Langley MR, Booker JK, Evans JP, McLeod HL, Weck KE. J Mol Diagn. May 2009
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New Product

The Warfarin Genotyping Reagents are new products. It is compatible with both the LightScanner® and HR-1® instruments.


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